Tyler Cowen puts forward an argument suggesting that being "reasonable" might actually dampen innovation. This make intuitive sense: path breaking ideas (think Copernicus' Heavenly Bodies and Darwin's Origin of Species) attack the conventional wisdom, make people uncomfortable, and are therefore seen as "unreasonable."
Now, I don't think we're expecting highly unreasonable people like Bill O'Reilly to burst forth with pearls of wisdom any time soon, but it's an interesting argument all the same. Quite what this means for IPE Journal's goal of pushing the debate towards a 'reasonable' paradigm on political economy remains to be seen.
In the meantime, quirky geniuses who took "unreasonable" to whole new levels.